2018-12-18 16:31:422025-05-15 01:32:05
description
transcriptional repressor (CcpN family) of gluconeogenetic genes and of sr1. repression in the presence of glucose
transcriptional repressor (CcpN family) of gluconeogenetic genes and of [[gene|sr1]], repression in the presence of glucose, involved in the control of cell elongation
locus
BSU25250
BSU_25250
geneLength
636
639
outlinks
bsu
BSU25250
BSU_25250
Gene
Coordinates
2,604,959 → 2,605,597
2,604,959 2,605,597
The protein
[SW|Domains]
2 [SW|CBS domain]s (83-139, 148-211)
[SW|HTH deoR-type domain] (aa 6-70) (according to UniProt)
2 [SW|CBS domain]s (aa 83-139, aa 148-211) (according to UniProt)
Biological materials
Mutant
MGNA-C493 (yqzB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2491 NBRP B. subtilis, Japan]
DB104 ''ccpN''::cat, available in [SW|Sabine Brantl]'s lab
GP1128 ''ccpN''::cat, available in [SW|Jörg Stülke]'s lab
BKE25250 (Δ[[gene|ccpN]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE25250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCACCTTTTCACTTCATA, downstream forward: _UP4_TAAGATTGCAAACTAACGGG
BKK25250 (Δ[[gene|ccpN]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK25250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCACCTTTTCACTTCATA, downstream forward: _UP4_TAAGATTGCAAACTAACGGG
MGNA-C493 (yqzB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2491 NBRP B. subtilis, Japan]
DB104 ''ccpN''::cat, available in [SW|Sabine Brantl]'s lab
GP1128 ''ccpN''::cat, available in [SW|Jörg Stülke]'s lab
BKE25250 ([[gene|ccpN]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE25250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCACCTTTTCACTTCATA, downstream forward: _UP4_TAAGATTGCAAACTAACGGG
BKK25250 ([[gene|ccpN]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK25250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCACCTTTTCACTTCATA, downstream forward: _UP4_TAAGATTGCAAACTAACGGG
labs
[SW|Stephane Aymerich], Microbiology and Molecular Genetics, INRA Paris-Grignon, France
[SW|Sabine Brantl], Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany [http://www.uni-jena.de/AG_Bakteriengenetik_(_Doz__Dr__Sabine_Brantl_).html homepage]
[SW|Uwe Sauer], ETH Zürich, Switzerland [http://www.imsb.ethz.ch/researchgroup/sauer homepage]
[SW|Stephane Aymerich], Microbiology and Molecular Genetics, INRA Paris-Grignon, France
[SW|Sabine Brantl], Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany [http://www.uni-jena.de/AG_Bakteriengenetik_(_Doz__Dr__Sabine_Brantl_).html homepage]
[SW|Uwe Sauer], ETH Zrich, Switzerland [http://www.imsb.ethz.ch/researchgroup/sauer homepage]
References
Original Publications
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|3FV6] (the [SW|CBS domain]s, aa 63 ... 212)